KDE may refer to:
- KDE, an international free software community
- KDE Projects
- KDE e.V., the German foundation behind KDE
- KDE Plasma, graphical environments provided by KDE
- Kentucky Department of Education
- 4Kids Entertainment, NYSE stock ticker symbol
- Kernel density estimation
- Konami Digital Entertainment, the video game development and publishing subsidiary of Konami
- Makonde language (ISO 639-3:
kde)